sr bi sirna (Santa Cruz Biotechnology)
Structured Review

Sr Bi Sirna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sr+bi+sirna/SR-B1+siRNA/pmc12398886-65-18-21
Average 91 stars, based on 5 article reviews
Images
1) Product Images from "Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects"
Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects
Journal: Materials Today Bio
doi: 10.1016/j.mtbio.2025.102202
Figure Legend Snippet: Role of SR-B I and cholesterol efflux in the anti-inflammatory properties of Por-NPs in macrophages . iBMDMs were transfected with SR-BI siRNA (100 nM) to knockdown SR-BI. RT-qPCR measurement of (A) Il1b mRNA and (B) Ccl5 mRNA following incubation with discoidal Por-NPs and stimulation with LPS (10 ng/mL) (n = 3 biological replicates). iBMDMs were pre-incubated with PBS, methyl-β-cyclodextrin (MβCD, 4 % v/v), discoidal or CO-loaded Por-NPs (10 μg/mL) then stimulated with LPS (10 ng/mL) before RT-qPCR quantification of the mRNA levels of (C) Il1b and (D) Ccl5 . The nuclear fractions of (E) unstimulated and (F) LPS-stimulated iBMDMs were isolated and nuclear p65-NFκB protein levels (∼65 kDa) were assessed by Western blotting (n = 5–6 biological replicates). TATA binding protein (TBP, 37 kDa) was used as the nuclear protein loading control. Data expressed as Mean ± SD. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001, ∗∗∗∗ P < 0.0001 by one-way ANOVA with post-hoc Tukey's multiple comparisons.
Techniques Used: Transfection, Knockdown, Quantitative RT-PCR, Incubation, Isolation, Western Blot, Binding Assay, Control
Related Articles
Control:Article Title: Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I. Article Snippet: Author’s Accepted Manuscript Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I Zhou-Yi Wu, Hu Li, Jian-Rui Li, Xiao-Qin Lv, Jian-Dong Jiang, Zong-Gen Peng PII: S0014-2999(19)30193-1 DOI: https://doi.org/10.1016/j.ejphar.2019.03.033 Reference: EJP72291 To appear in: European Journal of Pharmacology Received date: 25 November 2018 Revised date: 8 March 2019 Accepted date: 18 March 2019 Cite this article as: Zhou-Yi Wu, Hu Li, Jian-Rui Li, Xiao-Qin Lv, Jian-Dong Jiang and Zong-Gen Peng, Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I , European Journal of Pharmacology, https://doi.org/10.1016/j.ejphar.2019.03.033 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Article Title: Multifunctional biomimetic porphyrin-lipid nanoparticles – novel nanoscale theranostics for atherosclerotic cardiovascular disease Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs using ELISAs for IL-1β and CCL5 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Incubation:Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Article Title: Multifunctional biomimetic porphyrin-lipid nanoparticles – novel nanoscale theranostics for atherosclerotic cardiovascular disease Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs using ELISAs for IL-1β and CCL5 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Transfection:Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Article Title: Multifunctional biomimetic porphyrin-lipid nanoparticles – novel nanoscale theranostics for atherosclerotic cardiovascular disease Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs using ELISAs for IL-1β and CCL5 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or Concentration Assay:Article Title: Theranostic porphyrin nanoparticles identify atherosclerosis via multimodal imaging and elicit atheroprotective effects Article Snippet: Secreted proteins were measured in cell culture supernatants from treated iBMDMs and in mouse plasma using ELISAs for IL-1β, CCL5 and CCL17 (Quantikine®, R&D systems). .. iBMDMs were incubated with transfection reagent alone (Lipofectamine® RNAiMAX, 13778150, Thermofisher), scrambled control siRNA (sc-37007, Santa Cruz) or |
